The principal objective of the course is to provide the students with an in-depth insight into the basic processes that govern the disposition of drugs and other xenobiotics by the human body and the correlation with efficacy and toxicity. The course focuses on the application of the principles of pharmacokinetics on solving problems in new drug discovery and development and the development of the herbal medicine products.
Real-world cases will be reviewed and formal readings and discussions will be carried out throughout the course to foster critical thinking and independent learning.
Pre-requisite: Participants need to have knowledge in biological sciences, pharmaceutical sciences, mathematics
Intended Learning Outcomes
CILO-1: Describe principles of pharmacokinetics and how it affects the hits in drug discovery and development.
CILO-2: Design and carry out in vivo and in vitro experiments to characterize ADME properties of selected compounds.
CILO-3: Analyze and model pharmacokinetic data and interpret pharmacokinetics data, correlate the data to efficacy and toxicity, and apply the ADME knowledge of the target compound to efficacy and toxicity studies.
CILO-4: Identify and solve practical problems with pharmacokinetics knowledge.
CILO-5: Discover and verify ADME knowledge through computational analysis.
CILO-6: Apply multidisciplinary knowledge and techniques to obtain in-depth pathophysiological basis of ADME.